Research Interests
Study of the early
stages of atherosclerosis, in particular the role of high fat diet
in eliciting endothelial dysfunction and inflamation of the brain
and kidney arterioles of LDL receptor null mice and the ensuing
parenchimal changes leading to functional impairment. We are
curently investigating the mechanisms by which these early events
are alleviated by the treatment with an oral apolipoprotein A
mimetic, D-4F. |