Curriculum Vitae
Research
Interest
My research interest is to study of the
mechanisms and control of atrial and ventricular fibrillation in
animal models using single cell microelectrode recordings and
optical mapping techniques of cardiac activation.
Representative
Publications
Ohara T, Qu, Z. Lee M-H, Ohara K, Ohara
K, Omichi C, Mandel WJ, Chen P-S, <
Karagueuzian HS. Increased vulnerability to inducible
atrial fibrillation caused by partial cellular uncoupling with
heptanol. Am J Physiol , 283:H1116-1122, 2002
Yashima M, Miyauchi Y, Cao J-M, Kim Y-H,
Mandel WJ, Chen P-S, Karagueuzian HS:
The mechanism of the probabilistic nature of ventricular
defibrillation threshold. Am J Physiol, 284: H249-255, 2003
Swissa M, Ohara T, Lee M-H, Kaul S, M.D.
Shah PK, Chen P-S, Karagueuzian HS:
Sildenafil-nitric oxide donor combination promotes ventricular
tachyarrhythmias in the swine right ventricle. Am J Physiol, Heart &
Circulatory Physiology, 282: H1787-1792, 2002
Miyauchi Y, Ohara K, Ohara T, Fishbein
MC, Zhou S, Lee MH, Mandel WJ, Chen P-S,
Karagueuzian HS: Altered atrial electrical restitution
and sympathetic hyperinnervation in hearts with chronic left
ventricular myocardial infarction. Implications to atrial
fibrillation. Circulation, 108:360-366, 2003
Miyauchi Y, Fishbein MC,
Karagueuzian HS: Electrical
current-induced atrial and pulmonary vein action potential duration
shortening and repetitive activity. Am J Physiol, Heart &
Circulatory Physiology, 287:H178-186, 2004
Miyauchi, M, Qu Z, Miyauchi Y, Zhou S-M,
Pak H, Mandel WJ, Fishbein MC, Chen P-S,
Karagueuzian HS: Chronic nicotine in hearts with healed
ventricular myocardial infarction promotes atrial flutter that
resembles typical human atrial flutter. Am J Physiol, Heart &
Circulatory Physiology, 288:H2878-H2886, 2005
Miyauchi Y, Hayashi H, Miyauchi M,
Okuyama Y, Mandel WJ, Chen P-S,
Karagueuzian HS: Heterogeneous pulmonary vein myocardial
cell repolarization: implications for reentry and triggered
activity. Heart Rhythm, 2:1339-1345, 2005 (Figure 1 of this paper
made the cover of the Journal and an editorial accompanied the
article)
Ono N, Hayashi H, Kawase A, Lin S-F, Li
H, Weiss JN, Chen P-S, Karagueuzian HS:
Spontaneous atrial fibrillation initiated by triggered activity near
the pulmonary veins in aged rats subjected to glycolytic inhibition.
Am J Physiol (Heart & Circulatory Physiology), 292:H639-H648, 2007.
(Figure 9 of this paper made the cover of the Journal)
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