Research
Interest
Vascular
and bone biology; role of lipids and oxidized lipids in
atherosclerosis and osteoporosis; signal transduction.
Representative
Publications
Parhami
F, Tintut Y, Goodman W, Beamer W, Demer LL: Atherogenic high
fat diet reduces bone mineralization in mice. J. Bone Miner Res.
16:182-188; 2001.
Parhami
F, Tintut Y, Ballard A, Fogelman AM, Demer LL: Leptin enhances
the calcification of vascular cells: Artery wall as a target of
leptin. Circulation Research 88:954-960; 2001.
Parhami
F, Garfinkel A, Demer LL: Role of lipids in osteoporosis.
Arterioscl. Thromb. Vascul. Biol. 20:2346-2348; 2000.
Parhami
F, Jackson SM, Tintut Y, Le V, Balucan JP, Territo MC, and
Demer LL: Atherogenic diet and minimally oxidized low density
lipoprotein inhibit osteogenic and promote adipogenic
differentiation of marrow stromal cells. J. Bone Miner Res,
14:2067-2078; 1999.
Parhami
F, Demer LL: Arterial calcification in face of osteoporosis in
ageing: can we blame oxidized lipids? Current Opinion in
Lipidology, 8:312-314; 1997.
Parhami
F, Morrow AD, Balucan JP, Leintinger N, Watson AD, Tintut Y,
Berliner JA, Demer LL: Lipid oxidation products have opposite
effects on calcifying vascular cell and bone cell differentiation:
A possible explanation for the paradox of arterial calcification
in osteoporotic patients. Arteriosclerosis, Thrombosis, Vasc.
Biol., 17:680-687, 1997.
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