Research
Interest
Mechanism and regulations of vascular and bone remodeling.
Representative
Publications
Huang MS, Morony S, Lu J, Zhang Z, Bezouglaia O, Tseng W, Tetradis
S, Demer LL, Tintut Y. Atherogenic phospholipids attenuate
osteogenic signaling by BMP-2 and PTH in osteoblasts.
J Biol Chem.
2007 May 22;
[Epub ahead of
print]
Jaffe IZ, Tintut Y, Newfell BG, Demer LL, Mendelsohn ME.
Mineralocorticoid receptor activation promotes vascular cell
calcification.
Arterioscler Thromb Vasc Biol.
2007; 27:799-805.
Tintut Y, Demer L. Role of osteoprotegerin and its ligands and
competing receptors in atherosclerotic calcification.
J Investig Med.
2006;54:395-401. Review.
Lin TC, Tintut Y, Lyman A, Mack W, Demer LL, Hsiai TK.
Mechanical response of a calcified plaque model to fluid shear
force. Ann Biomed
Eng.
2006;34:1535-41.
Demer LL, Tintut Y. Pitting phosphate transport inhibitors
against vascular calcification.
Circ Res.
2006;98:857-9.
Abedin M, Lim J, Tang TB, Park D, Demer LL, Tintut Y.
N-3 fatty acids inhibit vascular calcification via the
p38-mitogen-activated protein kinase and peroxisome proliferator-activated
receptor-gamma pathways.
Circ Res.
2006;98:727-9.
Demer LL, Tintut Y. Return to ectopia: stem cells in the artery
wall. Arterioscler
Thromb Vasc Biol.
2005;25:1307-8.
Tintut Y, Abedin M, Cho J, Choe A, Lim J, Demer LL. Regulation
of RANKL-induced osteoclastic differentiation by vascular cells.
J Mol Cell Cardiol.
2005;39:389-93.
Radcliff K, Tang TB, Lim J, Zhang Z, Abedin M, Demer LL, Tintut Y.
Insulin-like growth factor-I regulates proliferation and
osteoblastic differentiation of calcifying vascular cells via
extracellular signal-regulated protein kinase and
phosphatidylinositol 3-kinase pathways.
Circ Res.
2005;96:398-400.
Abedin M, Tintut Y, Demer LL. Mesenchymal stem cells and the
artery wall. Circ
Res.
2004;95:671-6. Review.
Garfinkel A, Tintut Y, Petrasek D, Bostrom K, Demer LL.
Pattern formation by vascular mesenchymal cells.
Proc Natl Acad Sci U S A.
2004;101:9247-50.
Abedin M, Tintut Y, Demer LL. Vascular calcification: mechanisms
and clinical ramifications.
Arterioscler Thromb Vasc
Biol.
2004;24:1161-70.
Tintut Y, Morony S, Demer LL. Hyperlipidemia promotes
osteoclastic potential of bone marrow cells ex vivo.
Arterioscler Thromb Vasc Biol.
2004;24:e6-10. |
