Curriculum Vitae

Research Interest

Oxidized lipoproteins and atherosclerosis

Representative Publications

Jung, M.E., J.A. Belriner, D. Angst, D. Yue, L. Koroniak, A.D. Watson, and R. Li, Total synthesis of the epoxy isoprostane phospholipid PEIPC and PECPC, Org. Lett., 7:3933-3935, 2005.

Berliner, J.A., and A.D. Watson, A role for oxidized phospholipids in atherosclerosis, N. Eng. J. Med., 353:8-11, 2005.

Berliner, J.A., G. Subbanagounder, N. Leitinger, A. D. Watson, and D. Vora, Evidence for a role of phospholipid oxidation products in atherogenesis, Trends Cardiovasc. Med., 11:142-147, 2001.

Navab, M., J. A. Berliner, G. Subbanagounder, S. Hama, A. J. Lusis, L. W. Castellani, S. Reddy, D. Shih, W. B. Shi, A. D. Watson, B. J. Van Lenten, D. Vora, and A. M. Fogelman, HDL and the inflammatory response induced by LDL-derived oxidized phospholipids, Arterioscler., Thromb., Vasc. Biol., 21:481-488, 2001.

Subbanagounder, G., N. Leitinger, D. C. Schwenke, J. W. Wong, H. Lee, C. Rizza, A. D. Watson, K. F. Faull, and J. A. Berliner, Determinants of the bioactivity of oxidized phospholipids: Specific oxidized fatty acyl groups at the sn-2 position, Arterioscl. Thromb. Vasc. Biol., 20:2248-2254, 2000.

Navab, M., S. Y. Hama, G. M. Ananthramaiah, K. Hassan, G. Hough, A. D. Watson, K. F. Faull, G. C. Fonarow, and A. M. Fogelman, Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized LDL - Steps 2 & 3, J. Lipid Res., 41:1495-1508, 2000.

Subbanagounder, G., A. D. Watson, and J. A. Berliner, Bioactive products of phospholipid oxidation: identification, measurement, and activities, Free Rad. Biol. Med., 28:1751-1761, 2000.

Jung, M.E., Berliner, J.A., Koroniak, L., Gugiu, B.G., and Watson, A.D., Improved synthesis of the epoxy isoprostane PEIPC and its reactivity with amines, Org. Lett., 10:4207-4209, 2008.

Cruz, D., Watson, A.D., Miller, C.S., Montoya, D., Ochoa, M.T., Sieling, P.A., Gutierrez, M.A., Navab, M., Reddy, S.T., Witztum, J.L., Fogelman, A.M., Rea, T.H., Eisenberg, D., Berliner, J.A., and Modlin, R.L., Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy, J. Clin. Invest., 118:2917-2928, 2008.

Navab, M., Gharavi, N., and Watson, A.D., Inflammation and metabolic disorders, Curr. Opin. Clin. Nutr. Metab. Care, 11:459-464, 2008.

Gugiu, B.G., Mouillesseaux, K., Duong, V., Herzog, T., Hekimian, A., Koroniak, L., Vondriska, T.M., and Watson, A.D., Protein targets of oxidized phospholipids in endothelial cells, J. Lipid Res., 49:510-520, 2008.

Watson, A.D., Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Lipidomics: a global approach to lipid analysis in biological systems, J. Lipid Res., 47:2101-2111, 2006.